John Thompson Hoffman (1828 - 1888), was a politician who served as 78th Mayor of New York City (1866 to 1868) and 23rd Governor of New York State (1869 to 1873).

Hoffman was born in 1828 in Ossining, NY. After attending Union College he studied for his law degree and passed the bar in 1849 and entered into practice. He was a member of the Young Men’s Tammany Hall General Committee, a member of the New York State Democratic Central Committee, and served as New York City Recorder from 1861 to 1866. Hoffman served as mayor of New York City from 1866 to 1868. From 1866 to 1868 he was Grand Sachem, or leader, of the Tammany Hall organization.

In 1868, Hoffman was elected New York State Governor with the help of William “Boss” Tweed (1823-1878)  of Tammany Hall. Tammany Hall politicians secretly hoped Hoffman, might eventually win the United States presidency, but in 1871, with allegations of corruption circling, public support began to wane for the Tammany Machine. Hoffman’s presidential aspirations evaporated soon thereafter. In failing health, Hoffman journeyed abroad in search of a cure and died in Wiesbaden, Germany on March 24, 1888.